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妊娠晚期维生素A缺乏对血小板参数的影响

时间:2020-10-21    点击: 次    来源:网络    作者:佚名 - 小 + 大

【摘要】 目的:了解妊娠晚期孕妇维生素A 缺乏率及其对血小板参数的影响。方法:采用回顾性分析的方法,选取2016 年10 月-2018年3 月来笔者所在医院分娩的1 314 例孕妇,在入院分娩时均抽取静脉血检测维生素A 浓度及血常规,所得数据采用SPSS 24.0 软件进行统计
学分析。结果:正常妊娠晚期孕妇维生素A 缺乏率为15.60%(205/1 314),非高龄产妇组和高龄产妇组缺乏率比较差异无统计学意义( 字2=0.416,P=0.519);两组孕妇维生素A 水平及血小板参数比较差异无统计学意义(P>0.05)。维生素A 正常组及缺乏组PLT 计数分别为(230.48±55.33)×109/L和(218.80±56.77)×109/L,MPV 分别为(9.82±1.16)fl 和(10.19±1.10)fl,PDW 分别为(11.41±2.49)% 和(12.12±2.36)%,比较差异均有统计学意义(P<0.05)。维生素A 缺乏导致MPV 异常的OR 值为0.529[P=0.000,95%CI(0.371,0.755)]。结论:笔者所在医院妊娠晚期孕妇维生素A 缺乏比例较高,可导致血小板降低,MPV 及PDW 升高,且是MPV 升高的中度相关因素,表明妊娠期有必要定期监测维生素A 浓度及血小板参数。
  【关键词】 妊娠; 维生素A; 血小板参数
  doi:10.14033/j.cnki.cfmr.2019.01.076 文献标识码 B 文章编号 1674-6805(2019)01-0159-02
  Vitamin A deficiency in Late Pregnancy and its Effect on Platelet Parameters/LIU Weidi, JIANG Hong, MO Shaoling, et al.//Chinese andForeign Medical Research,2019,17(1):159-160
【Abstract】 Objective:To understand the incidence of vitamin A deficiency and its effect on platelet parameters in late pregnancy.Method:Retrospectiveanalysis of 1 314 pregnant women who came to our hospital from October 2016 to March 2018 was made.All pregnant women take venous blood test for Vitamin Aconcentration and blood routine during the hospital delivery.Statistical analysis was performed by SPSS 24.0.Result:The incidence of vitamin A deficiency was 15.60%(205/1 314),and there was no difference in Vitamin A deficiency in elderly and non-elderly women( 字2=0.416,P=0.519);and the levels of Vitamin A and platelet parameters were not statistically significant in both groups(P<0.05).The blood platelet count in Vitamin A normal and deficiency group was (230.48±55.33)×109/L and (218.80±56.77)×109/L,while MPV was (9.82±1.16)fl and (10.19±1.10)fl,PDW was (11.41±2.49)% and (12.12±2.36)%,respectively,there were statistical differences.Vitamin A deficiency led to abnormal MPV,the OR value was 0.529[P=0.000,95%CI(0.371,0.755)].Conclusion: The incidence of vitamin A deficiency was still high in normal late pregnant women.A deficiency can lead to decreased PLT count,increased MPV and PDW,and it is a moderately correlated factor in the increase of MPV,and it may be associated with preeclampsia.It is necessary to regularly monitor Vitamin A concentration and platelet
parameters during pregnancy.
  【Key words】 Pregnancy; Vitamin A; Platelet parameter
  First-author’s address:Dongguan Traditional Chinese Medicine Hospital,Dongguan 523006,China

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